Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 5/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2619826 | 0.80 | BACE1 (0.34) | HDAC4BACE1BACE2DPP4 | |
| SCHEMBL8023134 | 0.80 | BACE1 (0.34) | HDAC4BACE1BACE2DPP4 | |
| SCHEMBL2109978 | 0.76 | EPHX1 (0.42) | — | |
| SCHEMBL2108345 | 0.74 | HDAC4 (0.31) | HDAC4BACE1 | |
| SCHEMBL8515221 | 0.73 | BACE1 (0.35) | HDAC4BACE1BACE2DPP4 | |
| SCHEMBL8515218 | 0.73 | BACE1 (0.35) | HDAC4BACE1BACE2DPP4 | |
| SCHEMBL2966687 | 0.71 | BACE1 (0.39) | HDAC4BACE1BACE2 | |
| SCHEMBL12690000 | 0.71 | BACE1 (0.39) | HDAC4BACE1BACE2 | |
| SCHEMBL2619831 | 0.71 | BACE1 (0.39) | HDAC4BACE1BACE2 | |
| SCHEMBL2108227 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233474-B1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2015-08-05 | — | — | EP | disclosed |