⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20397638 | 0.80 | — | — | |
| SCHEMBL7277124 | 0.80 | — | — | |
| SCHEMBL31030153 | 0.80 | — | — | |
| SCHEMBL13531175 | 0.80 | — | — | |
| SCHEMBL14699924 | 0.78 | — | — | |
| SCHEMBL9639592 | 0.78 | TSHR (0.43) | — | |
| SCHEMBL15998220 | 0.78 | — | — | |
| SCHEMBL13451806 | 0.78 | — | — | |
| SCHEMBL23544799 | 0.76 | TSHR (0.48) | — | |
| SCHEMBL18271527 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2902489-A1 | FGFR3 FUSION GENE AND PHARMACEUTICAL DRUG TARGETING SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2015-08-05 | — | — | EP | disclosed |