⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5650156 | 0.75 | — | — | |
| SCHEMBL8000387 | 0.69 | — | — | |
| SCHEMBL3284375 | 0.67 | — | — | |
| SCHEMBL169840 | 0.65 | — | — | |
| SCHEMBL10130761 | 0.63 | — | — | |
| SCHEMBL9340044 | 0.63 | — | — | |
| SCHEMBL8915265 | 0.63 | — | — | |
| SCHEMBL8012547 | 0.63 | — | — | |
| SCHEMBL2446 | 0.63 | — | — | |
| SCHEMBL2843474 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239954-A1 | SEVEN-MEMBERED RING COMPOUNDS AND METHOD OF USE THEREOF | INVEA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | claimed |
| US-20230398124-A1 | SEVEN-MEMBERED RING COMPOUNDS AND METHOD OF USE THEREOF | INVEA THERAPEUTICS INC (US) | 2023-12-14 | — | — | US | claimed |
| CN-116829995-A | Liquid crystal composition, cured film, polarizing plate, and image display device | 富士胶片株式会社 | 2023-09-29 | — | — | CN | claimed |
| WO-2020070050-A1 | FUNGICIDAL 5-SUBSTITUTED IMIDAZOL-1-YL CARBINOL DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-04-09 | — | — | WO | claimed |
| WO-2019162228-A1 | 1-(5-SUBSTITUTED IMIDAZOL-1-YL)BUT-3-EN DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2019-08-29 | — | — | WO | claimed |
| EP-3519405-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLOXIRANE DERIVATIVES AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-07 | — | — | EP | claimed |
| EP-3519408-A1 | 1 -[2-(1 -CHLOROCYCLOPROPYL)-2-HYDROXY-3-(3-PHENYL-1,2-OXAZOL-5-YL)PROPYL]-1H-IMIDAZOLE-5-CARBONITRILE DERIVATIVES AND RELATED COMPOUNDS AS FUNGICIDES FOR CROP PROTECTION | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-07 | — | — | EP | claimed |
| EP-3519404-A1 | 5-SUBSTITUTED IMIDAZOLYLMETHYLDIOXOLANE DERIVATIVES AS FUNGICIIDES | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-07 | — | — | EP | claimed |
| EP-2733141-B1 | AZABENZIMIDAZOLE DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY | SHIONOGI & CO (JP) | 2019-01-09 | — | — | EP | claimed |
| US-20180186814-A1 | TRICYCLIC COMPOUND HAVING SULFINYL OR SULFONYL | SHIONOGI & CO., LTD. (JP) | 2018-07-05 | — | — | US | claimed |
| WO-2004071507-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2004-08-26 | — | — | WO | claimed |
| US-6407104-B1 | Pyrrolo[1,2-a]pyrazine spla2 inhibitor | SHIONOGI & CO., LTD. (JP) | 2002-06-18 | — | — | US | claimed |
| WO-2001066111-A1 | COMPOSITIONS CONTAINING POTENTIAL SPLA2 INHIBITORS FOR THE TREATMENT OF PAIN | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | claimed |
| EP-1085021-A1 | PYRROLO 1,2-b]PYRIDAZINE DERIVATIVES HAVING sPLA 2? INHIBITORY EFFECT | SHIONOGI & CO., LTD. (JP) | 2001-03-21 | — | — | EP | claimed |
| EP-1066290-A1 | PYRROLO[1,2-a]PYRAZINE sPLA 2 INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2001-01-10 | — | — | EP | claimed |
| WO-1999051605-A1 | PYRROLO[1,2-a]PYRAZINE sPLA2 INHIBITOR | SHIONOGI & CO., LTD. (JP) | 1999-10-14 | — | — | WO | claimed |
| EP-0885004-A1 | USE OF 4-PHENYL-3,6-DIHYDRO-2H-PYRIDYL DERIVATIVES AS NMDA RECEPTOR SUBTYPE BLOCKERS | F.HOFFMANN-LA ROCHE AG (CH) | 1998-12-23 | — | — | EP | claimed |
| WO-1997032581-A1 | USE OF 4-PHENYL-3,6-DIHYDRO-2H-PYRIDYL DERIVATIVES AS NMDA RECEPTOR SUBTYPE BLOCKERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-12 | — | — | WO | claimed |
| US-5169749-A | Ballasted Schiff-type dye formed by reaction of aromatic primary amine developer and the deprotected leaving group; sharpness; efficiency | KONICA CORPORATION (JP) | 1992-12-08 | — | — | US | claimed |
| EP-0452883-A2 | Silver halide photographic materials | KONICA CORPORATION (JP) | 1991-10-23 | — | — | EP | claimed |