SCHEMBL169846

SCHEMBL169846

C=CCOS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.44
TLR9 Q9NR96 1/20 0.44
GAA P10253 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
STAT3 P40763 1/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CA3 P07451 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA5B Q9Y2D0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28664754 0.98 C5AR1 (0.43) C5AR1TLR9GAANPSR1STAT3
Ammonia Solution, Strong SCHEMBL12478377 0.98 C5AR1 (0.43) C5AR1TLR9GAANPSR1STAT3
Trimethylammonium SCHEMBL4908728 0.95 C5AR1 (0.44) C5AR1TLR9GAANPSR1STAT3
SCHEMBL14780436 0.93 C5AR1 (0.40) C5AR1TLR9GAANPSR1STAT3
Alcohol SCHEMBL11289368 0.93 NPSR1 (0.42) C5AR1TLR9GAANPSR1STAT3
Ether SCHEMBL12487654 0.92 C5AR1 (0.39) C5AR1TLR9GAANPSR1STAT3
SCHEMBL27597410 0.90 CA1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL9703417 0.88 C5AR1 (0.43) C5AR1GAANPSR1STAT3CA12
SCHEMBL11282649 0.88 CNR2 (0.47) C5AR1GAACA12CA9SMN1; SMN2
SCHEMBL9324283 0.86 TLR9 (0.41) C5AR1TLR9GAANPSR1STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4857 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4656669-A1 FLUORINATED COPOLYMERS BASED ON AN OLIGO(2-OXAZOLINE) MACROMONOMER ARKEMA FRANCE (FR) 2025-12-03 EP claimed
CN-119920824-A Lithium battery positive electrode, preparation method thereof and solid-state battery 重庆太蓝新能源有限公司 2025-05-02 CN claimed
CN-118930427-A Preparation method of (2E) -4-ethylheptyl-2, 6-dienoic acid 南京正济医药研究有限公司 2024-11-12 CN claimed
CN-118354842-A Janus type spherical cellulose nano-particles 奥克兰理工大学投资有限公司 2024-07-16 CN claimed
EP-3674298-B9 SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS Bayer Pharma AG (DE) 2024-06-19 EP claimed
CN-117776887-A Preparation method of cyclopropyl methyl ketone 浙江大学 2024-03-29 CN claimed
CN-117623975-A Allyl-containing alpha-quaternary carbon secondary amine compound and oxazine compound synthesized by same and containing quaternary carbon center 扬州大学 2024-03-01 CN claimed
CN-117567252-A Method for preparing perfluoro isobutyl ether by hexafluoropropylene dimer phase transfer catalysis 浙江巨化汉正新材料有限公司 2024-02-20 CN claimed
US-11901508-B2 Silicon-based energy storage devices with functionalized linear sulfonate ester derivative compound containing electrolyte additives ENEVATE CORPORATION (US) 2024-02-13 US claimed
CN-117425652-A Novel salts and crystals 细胞内治疗公司 2024-01-19 CN claimed
EP-0155492-A1 Preparation of 1-alkyl-3,5-diphenylpyrazoles AMERICAN CYANAMID COMPANY (US) 1985-09-25 EP claimed
US-4543440-A AROMATIC PRIMARY DIAMINE AS CURING AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-09-24 US claimed
EP-0141345-A2 Process for producing cross-linked resins Takeda Chemical Industries, Ltd. (JP) 1985-05-15 EP claimed
EP-0140291-A2 Process for producing cross-linked polyesteramides Takeda Chemical Industries, Ltd. (JP) 1985-05-08 EP claimed
EP-0118312-A2 Curable polymeric compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-09-12 EP claimed
EP-0027646-B1 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1984-03-07 EP claimed
EP-0031253-B1 PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP claimed
EP-0031253-A1 Process for preparing 3,4-substituted benzaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-01 EP claimed
US-4111859-A METHOD OF PREPARATION OF ION EXCHANGERS BY ALKYLATION AND HYDROXYALKYLATION OF POLYMERIC HYDROPHILIC ANION EXCHANGERS CESKOSLOVENSKA AKADEMIE VED (CS) 1978-09-05 US claimed
US-3963736-A Preparation of 1-(lower alkyl)-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acids SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-06-15 US claimed