Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 14/20 | 0.58 |
| ▸ | CSF1R | P07333 | 11/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698662 | 0.97 | FLT3 (0.55) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| Hydrochloric Acid SCHEMBL1698622 | 0.87 | FLT3 (0.73) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| SCHEMBL1698852 | 0.86 | FLT3 (0.57) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| SCHEMBL1698969 | 0.86 | FLT3 (0.79) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| SCHEMBL1698709 | 0.83 | FLT3 (0.74) | FLT3CSF1RRAF1PDGFRBKIT | |
| SCHEMBL1698859 | 0.82 | FLT3 (0.75) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| SCHEMBL1698945 | 0.82 | FLT3 (0.75) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| SCHEMBL1698903 | 0.78 | FLT3 (0.78) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| SCHEMBL12067859 | 0.78 | FLT3 (0.62) | FLT3CSF1RMAPK14RAF1PDGFRB | |
| Hydrochloric Acid SCHEMBL9978805 | 0.78 | FLT3 (0.61) | FLT3CSF1RMAPK14RAF1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011150198-A1 | AZOLYL UREA COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |