2,4-Dihydroxybenzophenone

2,4-Dihydroxybenzophenone

SCHEMBL1699129

O=C(c1ccccc1)c1ccc(O)cc1O.O=C(c1ccccc1)c1ccc(O)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 1.00
KMT2A Q03164 6/20 1.00
USP2 O75604 1/20 1.00
GAA P10253 1/20 1.00
KEAP1 Q14145 1/20 1.00
NFE2L2 Q16236 1/20 1.00
HPGD P15428 6/20 0.67
ALDH1A1 P00352 5/20 0.67
LMNA P02545 3/20 0.67
MAPK1 P28482 2/20 0.67
CYP1A2 P05177 2/20 0.67
CYP2D6 P10635 2/20 0.67
PGR P06401 1/20 0.67
SLC6A2 P23975 1/20 0.67
PDE4A P27815 1/20 0.67
CYP2C19 P33261 1/20 0.67
HRH1 P35367 1/20 0.67
HTT P42858 1/20 0.67
SLC6A3 Q01959 1/20 0.67
PDE4D Q08499 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dihydroxybenzophenone SCHEMBL28179616 1.00 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL30201813 1.00 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL28108552 1.00 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL39681 1.00 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL29351647 1.00 MEN1 (1.00) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL1326734 0.98 MEN1 (0.96) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL26132519 0.98 MEN1 (0.96) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL11411345 0.98 MEN1 (0.96) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL27637079 0.98 MEN1 (0.96) MEN1KMT2AUSP2GAAKEAP1
2,4-Dihydroxybenzophenone SCHEMBL28274547 0.96 MEN1 (0.93) MEN1KMT2AUSP2GAAKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3675809-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS BASF SE (DE) 2020-07-08 EP disclosed
EP-3481365-A1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2019-05-15 EP disclosed
WO-2019043164-A1 USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS BASF SE (DE) 2019-03-07 WO disclosed
WO-2018007577-A1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2018-01-11 WO disclosed
EP-3229766-A1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2017-10-18 EP disclosed
EP-3128995-A1 SOLUBLIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2017-02-15 EP disclosed
EP-3104833-A1 CAPRYLOYL ALANINE ETHYLESTER AS A PENETRATION ENHANCEER BASF SE (DE) 2016-12-21 EP disclosed
EP-3041904-A1 STYRYL SULFIDE DYES BASF SE (DE) 2016-07-13 EP disclosed
WO-2016091930-A1 SOLUBILIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2016-06-16 WO disclosed
WO-2015155095-A1 SOLUBLIZING AGENTS FOR UV FILTERS IN COSMETIC FORMULATIONS BASF SE (DE) 2015-10-15 WO disclosed
EP-0907352-A1 METHOD AND COMPOSITION FOR SKIN LIGHTENING UNILEVER PLC (GB) 1999-04-14 EP disclosed
WO-1997047280-A1 METHOD AND COMPOSITION FOR SKIN LIGHTENING UNILEVER PLC (GB) 1997-12-18 WO disclosed
EP-0725623-A1 COSMETIC COMPOSITION COMPRISING A HYDROCALCHONE AND OPTIONALLY RETINOL OR A DERIVATIVE THEREOF UNILEVER PLC (GB) 1996-08-14 EP disclosed
EP-0713383-A1 SUNSCREEN AGENTS UNILEVER PLC (GB) 1996-05-29 EP disclosed
EP-0666735-A1 RETINOL CONTAINING COSMETIC COMPOSITION UNILEVER PLC (GB) 1995-08-16 EP disclosed
EP-0662818-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1995-07-19 EP disclosed
WO-1995011662-A1 COSMETIC COMPOSITION COMPRISING A HYDROCALCHONE AND OPTIONALLY RETINOL OR A DERIVATIVE THEREOF UNILEVER PLC (GB) 1995-05-04 WO disclosed
WO-1995005150-A1 SUNSCREEN AGENTS UNILEVER PLC (GB) 1995-02-23 WO disclosed
WO-1994009756-A1 RETINOL CONTAINING COSMETIC COMPOSITION UNILEVER PLC (GB) 1994-05-11 WO disclosed
WO-1994007462-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1994-04-14 WO disclosed