Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993176 | 0.91 | FGFR1 (0.51) | FGFR1FGFR2 | |
| SCHEMBL16993427 | 0.88 | FGFR1 (0.63) | FGFR1FGFR2 | |
| SCHEMBL16993332 | 0.88 | FGFR1 (0.50) | FGFR1FGFR2 | |
| SCHEMBL16993206 | 0.81 | FGFR1 (0.60) | FGFR1FGFR2 | |
| SCHEMBL16993401 | 0.79 | FGFR1 (0.64) | FGFR1FGFR2 | |
| SCHEMBL17910139 | 0.79 | FGFR1 (0.51) | FGFR1FGFR2 | |
| SCHEMBL16993028 | 0.78 | FGFR1 (0.63) | FGFR1FGFR2 | |
| SCHEMBL17968418 | 0.78 | FGFR1 (0.80) | FGFR1FGFR2 | |
| SCHEMBL17910146 | 0.76 | FGFR1 (0.63) | FGFR1FGFR2 | |
| SCHEMBL19499704 | 0.75 | FGFR1 (0.59) | FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102577-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | Principia Biopharma Inc. (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015120049-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA, INC. (US) | 2015-08-13 | — | — | WO | disclosed |