Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993316 | 1.00 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993228 | 1.00 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993158 | 0.96 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993160 | 0.96 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993315 | 0.96 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993073 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993074 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993336 | 0.94 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993095 | 0.90 | FGFR1 (1.00) | FGFR1FGFR2 | |
| SCHEMBL16993421 | 0.90 | FGFR1 (1.00) | FGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102577-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | Principia Biopharma Inc. (US) | 2016-12-14 | — | — | EP | claimed |
| WO-2015120049-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA, INC. (US) | 2015-08-13 | — | — | WO | claimed |
| EP-3102577-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | Principia Biopharma Inc. (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015120049-A1 | QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS | PRINCIPIA BIOPHARMA, INC. (US) | 2015-08-13 | — | — | WO | disclosed |