SCHEMBL169940

SCHEMBL169940

Cc1c(F)c(F)c(C(F)(F)F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19756809 0.94 SMN1; SMN2 (0.33) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL13798623 0.92 SMN1; SMN2 (0.32) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL19426930 0.91 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL26078255 0.88
SCHEMBL17151431 0.88 SMN1; SMN2 (0.33) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL3177638 0.88 SMN1; SMN2 (0.31) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL26568311 0.85 MEN1 (0.30) SMN1; SMN2MEN1KMT2A
SCHEMBL26078235 0.85 MEN1 (0.30) SMN1; SMN2MEN1KMT2A
SCHEMBL23963458 0.85 SMN1; SMN2 (0.31) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL14449319 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108164431-B 2-hydroxy-5- (2,3,5, 6-tetrafluoro-4-trifluoromethyl benzylamino) benzoic acid and preparation method thereof 浙江普洛家园药业有限公司 2021-10-08 CN claimed
CN-108164431-A 2- hydroxyls -5-(Tetra- fluoro- 4- benzylaminos of 2,3,5,6-)Benzoic acid and preparation method thereof 浙江普洛家园药业有限公司 2018-06-15 CN claimed
EP-0034731-B1 TRIFLUOROMETHYLBENZYLIC ESTERS, THEIR INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES BAYER AG (DE) 1985-10-30 EP claimed
WO-2024125835-A1 BLOCK COPOLYMER, METHOD FOR PRODUCING A BLOCK COPOLYMER, MEMBRANE, USE OF A MEMBRANE, AND METHOD FOR PRODUCING A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-06-20 WO disclosed
US-20230350294-A1 Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-02 US disclosed
US-20230350294-A1 Negative Photosensitive Resin Composition, Patterning Process, Interlayer Insulating Film, Surface Protection Film, And Electronic Component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-02 US disclosed
EP-4253389-A1 COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR Lg Chem, Ltd. (KR) 2023-10-04 EP disclosed
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
EP-3398983-B1 POLYMER OF POLYIMIDE PRECURSOR, POSITIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, NEGATIVE TYPE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC PARTS SHINETSU CHEMICAL CO (JP) 2023-09-27 EP disclosed
US-11768434-B2 Polymer having a structure of polyamide, polyamide-imide, or polyimide, photosensitive resin composition, patterning process, photosensitive dry film, and protective film for electric and electronic parts SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-26 US disclosed
WO-2023170131-A1 MATERIAL, METHOD FOR PRODUCING A MATERIAL, MEMBRANE, USE OF A MEMBRANE, ELECTRODE CATALYST LAYER AND USE OF A MATERIAL Forschungszentrum Jülich GmbH (DE) 2023-09-14 WO disclosed
US-7169879-B2 Bisphenyl-2,3,5,6-tetrafluoro-4-trifluoromethylphenyl phosphine oxide derivative and synthesis thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-01-30 US disclosed
EP-0623140-A1 NOVEL 19-NOR STEROIDS HAVING A THIOCARBON-CONTAINING CHAIN IN THE 11BETA POSITION, A METHOD FOR PREPARING SAME AND INTERMEDIATES THEREFOR, MEDICINAL USES THEREOF AND COMPOSITIONS CONTAINING SAID STEROIDS ROUSSEL UCLAF (FR) 1994-11-09 EP disclosed
WO-1993013123-A1 NOVEL 19-NOR STEROIDS HAVING A THIOCARBON-CONTAINING CHAIN IN THE 11BETA POSITION, A METHOD FOR PREPARING SAME AND INTERMEDIATES THEREFOR, MEDICINAL USES THEREOF AND COMPOSITIONS CONTAINING SAID STEROIDS ROUSSEL-UCLAF (FR) 1993-07-08 WO disclosed
US-4486355-A INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-12-04 US disclosed
EP-0032121-B1 SUBSTITUTED TETRAFLUOROBENZYL ALCOHOLS AND HALIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-05-16 EP disclosed
US-4385070-A CYCLOPROPANE DERIVATIVES AS INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1983-05-24 US disclosed
EP-0016513-B1 ESTERS OF HALOGENATED SUBSTITUTED CYCLOPROPANOIC ACIDS, THEIR PREPARATION AND USE AS INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-06-23 EP disclosed
EP-0032121-A2 Substituted tetrafluorobenzyl alcohols and halides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-07-15 EP disclosed
EP-0016513-A2 Esters of halogenated substituted cyclopropanoic acids, their preparation and use as insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 SMN1; SMN2 3293/4885TSHR 4318/4885MEN1 1630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.