Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239670 | 0.92 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL239669 | 0.92 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL2755381 | 0.92 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL238939 | 0.92 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL238940 | 0.92 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL2755152 | 0.92 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL234344 | 0.89 | AKT1 (0.51) | AKT1AKT2 | |
| SCHEMBL234345 | 0.89 | AKT1 (0.51) | AKT1AKT2 | |
| SCHEMBL2755223 | 0.78 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL239573 | 0.78 | AKT1 (0.49) | AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406250-B1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME (US) | 2015-08-12 | — | — | EP | disclosed |