SCHEMBL16996100

SCHEMBL16996100

Cc1ccccc1-c1ccc(N(c2ccc3c(c2)C(C)(C)c2ccccc2-3)c2ccc3c(c2)C(c2ccccc2)(c2ccccc2)c2ccccc2-3)cc1C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.38
▸ ESR2 Q92731 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ OPRK1 P41145 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ PDK2 Q15119 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16996136 0.94 ESR1 (0.42) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL808302 0.92 ESR1 (0.35) ESR1ESR2PDK2
SCHEMBL16996429 0.92 ESR1 (0.41) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL24750111 0.91 ESR1 (0.40) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL17804680 0.91 ESR1 (0.43) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL16996089 0.91 MEN1 (0.40) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL16996088 0.91 MEN1 (0.40) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL17854530 0.90 ESR1 (0.40) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL16996388 0.90 MEN1 (0.39) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL12722823 0.90 PDK2 (0.38) ESR1ESR2PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210002-A1 COMPOSITION, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 — — US disclosed
US-20230210002-A1 COMPOSITION, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 — — US disclosed
US-11575087-B1 Organic electroluminescence device, light emitting device, organic electroluminescence display device and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-02-07 — — US disclosed
US-20230036664-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, LIGHT EMITTING DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 — — US disclosed
US-20220285620-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-09-08 — — US disclosed
US-11362279-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-14 — — US disclosed
US-20210328156-A1 MIXTURE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-21 — — US disclosed
US-11069861-B2 Mixture, organic electroluminescence device and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2021-07-20 — — US disclosed
US-20210043850-A1 MIXTURE, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO.,LTD. (JP) 2021-02-11 — — US disclosed
US-20200321526-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD (JP) 2020-10-08 — — US disclosed
US-20200313090-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-10-01 — — US disclosed
US-10014477-B2 Aromatic amine derivative, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-07-03 — — US disclosed
US-20180123043-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2018-05-03 — — US disclosed
US-20150243891-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-08-27 — — US disclosed
US-20150243891-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2015-08-27 — — US disclosed
US-20150228899-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-08-13 — — US disclosed
US-20150228899-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-08-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200313090-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 ESR1 17/4885ESR2 16/4885KDM4E 299/4885
US-20220285620-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 ESR1 17/4885ESR2 16/4885KDM4E 299/4885
US-20180123043-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 ESR1 17/4885ESR2 16/4885KDM4E 299/4885
US-11362279-B2 Aromatic amine derivative, and organic electroluminescent element using same ASH2L, EHMT2, H1-2 ESR1 17/4885ESR2 16/4885KDM4E 299/4885
US-20150243891-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 ESR1 17/4885ESR2 16/4885KDM4E 299/4885
US-10014477-B2 Aromatic amine derivative, and organic electroluminescent element using same ASH2L, EHMT2, H1-2 ESR1 17/4885ESR2 16/4885KDM4E 299/4885
US-20200321526-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME ASH2L, EHMT2, H1-2 ESR1 17/4885ESR2 16/4885KDM4E 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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