SCHEMBL16997464

SCHEMBL16997464

Clc1cc(Cl)c(I)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15749443 0.81
SCHEMBL689954 0.79
SCHEMBL29411255 0.79
SCHEMBL898499 0.75
SCHEMBL31622334 0.75
SCHEMBL24809999 0.75
SCHEMBL31573408 0.75
SCHEMBL10200436 0.75
SCHEMBL16804981 0.75
SCHEMBL16333726 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577228-B2 Dihydrocyclopenta-isoquinoline-sulfonamide derivatives compounds UCB Biopharma SRL (BE) 2026-03-17 US disclosed
EP-4081296-B1 DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS UCB Biopharma SRL (BE) 2026-02-11 EP disclosed
US-20250270190-A1 KIT INHIBITORS BLUEPRINT MEDICINES CORPORATION 2025-08-28 US disclosed
US-12331237-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-06-17 US disclosed
US-12331065-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-06-17 US disclosed
WO-2025080788-A1 CCR4 INHIBITORS AND METHODS OF USE THEREOF RAYTHERA, INC. (US) 2025-04-17 WO disclosed
US-12258327-B2 5-membered heteroaryl-containing aminopyridine compounds as EGFR inhibitors YUHAN CORPORATION (KR) 2025-03-25 US disclosed
CN-119569635-A Biaryl ring inhibitors targeting c-Myc proteins 上海深势唯思科技有限责任公司 2025-03-07 CN disclosed
CN-119585250-A KIT inhibitors 蓝图药品公司 2025-03-07 CN disclosed
EP-4511366-A1 KIT INHIBITORS Blueprint Medicines Corporation (US) 2025-02-26 EP disclosed
EP-4081296-A1 DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS UCB Biopharma SRL (BE) 2022-11-02 EP disclosed
CN-114845778-A Dihydrocyclopentaisoquinoline sulfonamide derivative compound UCB生物制药有限责任公司 2022-08-02 CN disclosed
US-20220106344-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-07 US disclosed
WO-2021130259-A1 DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS UCB Biopharma SRL (BE) 2021-07-01 WO disclosed
US-20210098717-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 US disclosed
US-20210098717-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 US disclosed
CN-112552352-A Organic electroluminescent material and device 环球展览公司 2021-03-26 CN disclosed
WO-2017040766-A1 ANTI-VIRAL TETRAHYDROFURANE DERIVATIVES ABBVIE INC. (US) 2017-03-09 WO disclosed
US-20150225372-A1 5-(Pyridin-2-yl-Amino)-Pyrazine-2-Carbonitrile Compounds and Their Therapeutic Use CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2015-08-13 US disclosed
US-20150225372-A1 5-(Pyridin-2-yl-Amino)-Pyrazine-2-Carbonitrile Compounds and Their Therapeutic Use CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2015-08-13 US disclosed