Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17001789 | 1.00 | EPHX1 (0.49) | EPHX1HPGDHSD17B10ALDH1A1RECQL | |
| SCHEMBL31040357 | 0.96 | EPHX1 (0.51) | EPHX1HPGDHSD17B10ALDH1A1RECQL | |
| SCHEMBL20310655 | 0.85 | EPHX1 (0.48) | EPHX1HPGDHSD17B10ALDH1A1RECQL | |
| SCHEMBL17001716 | 0.85 | EPHX1 (0.48) | EPHX1HPGDHSD17B10ALDH1A1RECQL | |
| SCHEMBL21981304 | 0.85 | EPHX1 (0.41) | EPHX1HPGDHSD17B10ALDH1A1GPR119 | |
| SCHEMBL31633849 | 0.85 | NR1H2 (0.48) | EPHX1HPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL19273232 | 0.82 | HPGD (0.52) | EPHX1HPGDHSD17B10RECQLPTPN2 | |
| SCHEMBL18923615 | 0.82 | HPGD (0.52) | EPHX1HPGDHSD17B10RECQLPTPN2 | |
| SCHEMBL19946958 | 0.82 | EPHX1 (0.42) | EPHX1HPGDHSD17B10ALDH1A1RECQL | |
| SCHEMBL19946959 | 0.82 | EPHX1 (0.42) | EPHX1HPGDHSD17B10ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015118342-A1 | BICYCLIC AZA COMPOUNDS AS MUSCARINIC M1 RECEPTOR AGONISTS. | HEPTARES THERAPEUTICS LIMITED (GB) | 2015-08-13 | — | — | WO | disclosed |