SCHEMBL17004147

SCHEMBL17004147

NC(=O)Oc1cc(Br)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKT2 P31751 19/20 0.77
AKT1 P31749 19/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17004146 0.89 AKT1 (0.75) AKT2AKT1
SCHEMBL360121 0.87 AKT2 (1.00) AKT2AKT1
SCHEMBL360951 0.86 AKT2 (1.00) AKT2AKT1
SCHEMBL17004170 0.85 AKT1 (0.75) AKT2AKT1
SCHEMBL17004171 0.85 AKT1 (0.75) AKT2AKT1
SCHEMBL17004151 0.85 AKT2 (0.78) AKT2AKT1
SCHEMBL17004152 0.85 AKT2 (0.79) AKT2AKT1
SCHEMBL17004166 0.84 AKT2 (0.76) AKT2AKT1
SCHEMBL17004162 0.84 AKT1 (0.81) AKT2AKT1
SCHEMBL17004140 0.82 AKT2 (0.75) AKT2AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593451-B1 SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AND -PYRIDINES BAYER IP GMBH (DE) 2015-08-19 EP claimed