Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004345 | 0.88 | PDE2A (0.64) | PDE2AALDH1A1MAPTLMNAFASN | |
| SCHEMBL2681280 | 0.85 | PDE2A (0.75) | PDE2AALDH1A1MAPTLMNAFASN | |
| SCHEMBL2680045 | 0.83 | PDE2A (0.64) | PDE2AALDH1A1MAPTLMNAFASN | |
| SCHEMBL959342 | 0.83 | PDE2A (0.66) | PDE2AALDH1A1MAPTLMNAFASN | |
| SCHEMBL2680677 | 0.83 | PDE2A (0.68) | PDE2AALDH1A1MAPTLMNAFASN | |
| SCHEMBL936083 | 0.81 | PDE2A (0.67) | PDE2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL955665 | 0.79 | PDE2A (0.77) | PDE2AALDH1A1MAPTLMNAFASN | |
| SCHEMBL961087 | 0.79 | PDE2A (0.73) | PDE2AALDH1A1MAPTLMNASMPD3 | |
| SCHEMBL2680564 | 0.79 | PDE2A (0.67) | PDE2AALDH1A1MAPTLMNAFASN | |
| SCHEMBL6349005 | 0.79 | PDE2A (0.69) | PDE2AALDH1A1MAPTLMNAFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456440-B1 | QUINOLINONE PDE2 INHIBITORS | MERCK SHARP & DOHME (US) | 2015-08-19 | — | — | EP | claimed |