SCHEMBL17004394

C[C@H]1[C@@H](N(Cc2ccccc2)C2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(NCC5CCCCC5)c([N+](=O)[O-])c4)cc3)CC2)C[C@@H]2C[C@@H]1C2(C)C

nearest known ligand 0.48

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	BCL2L1	Q07817	19/20	0.48

▸	BCL2	P10415	14/20	0.48

▸	ALB	P02768	1/20	0.43

▸	BCL2L2	Q92843	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL17004393	1.00	BCL2L1 (0.48)	BCL2L1BCL2ALBBCL2L2
SCHEMBL2387538	0.91	BCL2L1 (0.48)	BCL2L1BCL2ALBBCL2L2
SCHEMBL2387542	0.91	BCL2L1 (0.48)	BCL2L1BCL2ALBBCL2L2
SCHEMBL2386759	0.91	BCL2L1 (0.49)	BCL2L1BCL2ALBBCL2L2
SCHEMBL2386756	0.91	BCL2L1 (0.49)	BCL2L1BCL2ALBBCL2L2
SCHEMBL2388939	0.90	BCL2L1 (0.47)	BCL2L1BCL2ALBBCL2L2
SCHEMBL2388935	0.90	BCL2L1 (0.47)	BCL2L1BCL2ALBBCL2L2
SCHEMBL19419640	0.89	BCL2L1 (0.47)	BCL2L1BCL2ALBBCL2L2
SCHEMBL2388417	0.89	BCL2L1 (0.47)	BCL2L1BCL2ALBBCL2L2
SCHEMBL17350552	0.89	BCL2L1 (0.47)	BCL2L1BCL2ALBBCL2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2550258-B1	APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES	ABBVIE INC (US)	2015-08-19	—	—	EP	claimed