Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 18/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385278 | 0.91 | BCL2 (0.59) | BCL2 | |
| SCHEMBL2384588 | 0.91 | BCL2 (0.59) | BCL2 | |
| SCHEMBL2386142 | 0.90 | BCL2 (0.58) | BCL2 | |
| SCHEMBL2390421 | 0.88 | BCL2 (0.56) | BCL2 | |
| SCHEMBL2385928 | 0.88 | BCL2 (0.56) | BCL2 | |
| SCHEMBL2385244 | 0.87 | BCL2 (0.55) | BCL2 | |
| SCHEMBL2388882 | 0.85 | BCL2 (0.53) | BCL2 | |
| SCHEMBL2388682 | 0.83 | BCL2 (0.51) | BCL2 | |
| SCHEMBL2388689 | 0.83 | BCL2 (0.51) | BCL2 | |
| SCHEMBL19424633 | 0.83 | BCL2 (0.50) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550258-B1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE INC (US) | 2015-08-19 | — | — | EP | claimed |