Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 15/20 | 0.94 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.94 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.79 |
| ▸ | PIK3R1 | P27986 | 11/20 | 0.79 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770694 | 0.99 | PIK3CB (0.92) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL3563102 | 0.97 | PIK3CB (1.00) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL31157034 | 0.92 | PIK3CB (0.90) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL477354 | 0.92 | PIK3CB (0.90) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL17011984 | 0.92 | PIK3CB (0.90) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL31157030 | 0.91 | PIK3CB (0.88) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL477252 | 0.91 | PIK3CB (0.88) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL477412 | 0.91 | PIK3CA (0.80) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL31157031 | 0.90 | PIK3CA (0.86) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG | |
| SCHEMBL477406 | 0.90 | PIK3CA (0.79) | PIK3CBPIK3CAPIK3CDPIK3R1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411387-B1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY | VETDC INC (US) | 2015-08-19 | — | — | EP | claimed |