Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007248 | 1.00 | HCRTR1 (0.56) | HCRTR1 | |
| SCHEMBL17028083 | 1.00 | HCRTR1 (0.56) | HCRTR1 | |
| Hydrochloric Acid SCHEMBL17007168 | 0.99 | HCRTR1 (0.55) | HCRTR1 | |
| Hydrochloric Acid SCHEMBL17028153 | 0.99 | HCRTR1 (0.55) | HCRTR1 | |
| Hydrochloric Acid SCHEMBL17007166 | 0.99 | HCRTR1 (0.55) | HCRTR1 | |
| SCHEMBL17021441 | 0.84 | HCRTR1 (0.57) | HCRTR1 | |
| SCHEMBL17007228 | 0.79 | HCRTR1 (0.69) | HCRTR1 | |
| SCHEMBL17017314 | 0.78 | SYK (0.46) | — | |
| SCHEMBL17007190 | 0.78 | HCRTR1 (0.49) | HCRTR1 | |
| SCHEMBL17021444 | 0.78 | HCRTR1 (0.59) | HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107898-B1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-01-06 | — | — | EP | disclosed |
| US-20150232460-A1 | NOVEL COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232460-A1 | NOVEL COMPOUNDS | CNKSR1, RDX, RB1 | HCRTR1 631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.