SCHEMBL170119

SCHEMBL170119

C=C1CCC(=O)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL65177 0.79 TRIM24 (0.54)
SCHEMBL806913 0.79
SCHEMBL8036939 0.78 TRIM24 (0.64)
SCHEMBL11074596 0.78
SCHEMBL8149187 0.78 TRIM24 (0.64)
SCHEMBL7645220 0.78 TRIM24 (0.64)
SCHEMBL2700307 0.78 TRIM24 (0.64)
SCHEMBL239887 0.78
SCHEMBL150852 0.78
SCHEMBL3440747 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1534689-A1 NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF BOEHRINGER INGELHEIM PHARMA GMBH &amp; CO. KG (DE) 2005-06-01 EP claimed
US-20040242572-A1 New carboxamide compounds having melanin concentrating hormone antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2004-12-02 US claimed
WO-2004024702-A1 NOVEL CARBOXAMIDE COMPOUNDS HAVING AN MCH-ANTAGONISTIC EFFECT, MEDICAMENTS CONTAINING SAID COMPOUNDS, AND METHODS FOR THE PRODUCTION THEREOF BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2004-03-25 WO claimed
US-20230250079-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-08-10 US disclosed
CN-116209664-A Small molecule modulators of IL-17 利奥制药有限公司 2023-06-02 CN disclosed
EP-4168114-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO Pharma A/S (DK) 2023-04-26 EP disclosed
US-20220003793-A1 Compounds and Methods for Use in Detecting Gabapentin ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2022-01-06 US disclosed
WO-2021250194-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2021-12-16 WO disclosed
US-10203345-B2 Compounds and methods for use in detecting gabapentin ARK DIAGNOSTICS, INC. (US) 2019-02-12 US disclosed
EP-2721004-B1 3-DESOXY-2-METHYLENE-19-NOR-VITAMIN D ANALOGS AND THEIR USES WISCONSIN ALUMNI RES FOUND (US) 2017-07-26 EP disclosed
US-20170138970-A1 Compounds and Methods for Use in Detecting Gabapentin ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2017-05-18 US disclosed
US-6127559-A 2-alkyl-19-nor-vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2000-10-03 US disclosed
EP-0971888-A1 2-ALKYL-19-NOR-VITAMIN D COMPOUNDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2000-01-19 EP disclosed
EP-0970047-A1 2-ALKYLIDENE-19-NOR-VITAMIN D COMPOUNDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2000-01-12 EP disclosed
US-5945410-A ADMINISTERED TO TREAT POSTMANOPAUSAL OSTEOPOROSIS, LOW BONE TURNOVER OSTEOPOROSIS, OSTEOMALACIA AND RENAL OSTEODYSTROPHY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1999-08-31 US disclosed
US-5936133-A USEFUL IN THEIR ABILITY TO MOBILIZE CALCIUM ION FROM THE BONE; ANTICARCINOGENIC AGENTS; USED FOR TREATING OSTEOPOROSIS, PROPHYLAXIS AND AUTOIMMUNE DISORDERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1999-08-10 US disclosed
WO-1998041500-A9 2-ALKYL-19-NOR-VITAMIN D COMPOUNDS 1999-03-04 WO disclosed
US-5843928-A 2-alkylidene-19-nor-vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-12-01 US disclosed
WO-1998041501-A1 2-ALKYLIDENE-19-NOR-VITAMIN D COMPOUNDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-09-24 WO disclosed
WO-1998041500-A1 2-ALKYL-19-NOR-VITAMIN D COMPOUNDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-09-24 WO disclosed