SCHEMBL170149

SCHEMBL170149

C=CCOCC(CO)OP(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.36
SMPD1 P17405 3/20 0.30
LPAR2 Q9HBW0 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2525977 1.00 CA1 (0.39) CA1CA2CA7CA9SMPD1
Choline SCHEMBL16267506 0.87 MEN1 (0.32) CA1CA2CA7
SCHEMBL8722298 0.86 CA1 (0.37) CA1CA2CA7CA9
SCHEMBL28412357 0.84 CA1 (0.38) CA1CA2CA7CA9
SCHEMBL958656 0.84 LPAR3 (0.40) CA1CA2CA7CA9LPAR2
SCHEMBL8015659 0.83 CA1 (0.35) CA1CA2CA7CA9
SCHEMBL7833013 0.83 CA1 (0.33) CA1CA2CA7CA9
SCHEMBL958655 0.83 CA1 (0.37) CA1CA2CA7CA9
SCHEMBL15290149 0.81 CA1 (0.36) CA1CA2CA7CA9SMPD1
SCHEMBL28066491 0.81 CA1 (0.36) CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130197038-A1 Compositions And Methods For Neovascularization MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-08-01 US claimed
US-20210315244-A1 COMPOUNDS THAT MODULATE GPR92 RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2021-10-14 US disclosed
EP-3846640-A1 COMPOUNDS THAT MODULATE GPR92 RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME Mars Incorporated (US) 2021-07-14 EP disclosed
US-10071110-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-09-11 US disclosed
US-20170239279-A1 PHOSPHONATE COMPOUNDS UNIV CALIFORNIA (US) 2017-08-24 US disclosed
US-9649321-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-05-16 US disclosed
US-9446031-B2 Compositions and methods for neovascularization NATIONAL UNIVERSITY OF SINGAPORE (SG) 2016-09-20 US disclosed
US-20160067268-A1 PHOSPHONATE COMPOUNDS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-03-10 US disclosed
US-9206208-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-12-08 US disclosed
US-20150051174-A1 Phosphonate Compounds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2015-02-19 US disclosed
EP-1233770-A4 PHOSPHONATE COMPOUNDS UNIV CALIFORNIA AT SAN DIEGO (US) 2003-04-16 EP disclosed
EP-1300426-A1 (Meth)acrylic acid type polymer and unsaturated polyalkylene glycol type copolymer, and methods for production thereof Nippon Shokubai Co., Ltd. (JP) 2003-04-09 EP disclosed
US-6451952-B2 POLYMERIZING ALLYL ETHER MONOMER IN PRESENCE OF HALOALKYL DIOXOLANE COMPOUND (BY-PRODUCT, IMPURITY); ANTISCALING AGENT WITH IMPROVED GELATION INHIBITION NIPPON SHOKUBAI CO., LTD. (JP) 2002-09-17 US disclosed
EP-1233770-A2 PHOSPHONATE COMPOUNDS The Regents of The University of California at San Diego (US) 2002-08-28 EP disclosed
US-20020049147-A1 Novel water-soluble copolymer and its production process and use NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-25 US disclosed
EP-1182217-A2 Novel water-soluble copolymer and its production process and use Nippon Shokubai Co., Ltd. (JP) 2002-02-27 EP disclosed
US-20020016430-A1 Production process for allyl ether-based polymer NIPPON SHOKUBAI CO., LTD. (JP) 2002-02-07 US disclosed
EP-1158009-A2 Production process for allyl ether-based polymer Nippon Shokubai Co., Ltd. (JP) 2001-11-28 EP disclosed
WO-2001039724-A2 PHOSPHONATE COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) 2001-06-07 WO disclosed
US-4500693-A OF (METH-)ACRYLIC ACID (OR SALT THEREOF) AND ALLYL ETHERSULFONATE NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1985-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051174-A1 Phosphonate Compounds PHPT1, PHOSPHO1, PIK3CA CA1 4092/4885CA2 3473/4885CA7 3176/4885
US-10071110-B2 Phosphonate compounds PHPT1, PHOSPHO1, PIK3CA CA1 4092/4885CA2 3473/4885CA7 3176/4885
US-20170239279-A1 PHOSPHONATE COMPOUNDS PHPT1, PHOSPHO1, PIK3CA CA1 4092/4885CA2 3473/4885CA7 3176/4885
US-20160067268-A1 PHOSPHONATE COMPOUNDS PHPT1, PHOSPHO1, PIK3CA CA1 4092/4885CA2 3473/4885CA7 3176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.