Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835688 | 0.89 | SPHK1 (0.46) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL3464686 | 0.87 | SPHK1 (0.42) | SPHK1HSD11B2BRD4HCRTR2GPR119 | |
| SCHEMBL3464690 | 0.87 | SPHK1 (0.42) | SPHK1HSD11B2BRD4HCRTR2GPR119 | |
| SCHEMBL15209134 | 0.85 | SPHK1 (0.48) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL15209132 | 0.85 | SPHK1 (0.48) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL12767436 | 0.84 | SPHK1 (0.47) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL21187940 | 0.84 | SPHK1 (0.47) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL27018596 | 0.83 | SPHK1 (0.41) | SPHK1HSD11B2BRD4CHRM2CHRM1 | |
| SCHEMBL10211270 | 0.83 | SPHK1 (0.45) | SPHK1HSD11B2BRD4HCRTR2CHRM2 | |
| SCHEMBL3390081 | 0.83 | SPHK1 (0.39) | SPHK1HSD11B2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123101-A1 | TREATMENT OF H. PYLORI INFECTIONS USING MTAN INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2015-08-20 | — | — | WO | disclosed |