Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17022414 | 1.00 | GAA (0.43) | GAAITGAL | |
| SCHEMBL17022362 | 1.00 | GAA (0.43) | GAAITGAL | |
| SCHEMBL17022308 | 1.00 | GAA (0.43) | GAAITGAL | |
| SCHEMBL17022426 | 0.95 | GAA (0.41) | GAAITGAL | |
| SCHEMBL17022400 | 0.95 | GAA (0.41) | GAAITGAL | |
| SCHEMBL17022383 | 0.94 | GAA (0.41) | GAA | |
| SCHEMBL17022305 | 0.92 | GAA (0.39) | GAA | |
| SCHEMBL17022339 | 0.92 | GAA (0.39) | GAAITGAL | |
| SCHEMBL17022418 | 0.91 | GAA (0.37) | GAA | |
| SCHEMBL17022437 | 0.90 | GAA (0.35) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015124663-A1 | ENANTIOPURE TETRASUBSTITUTED PYRROLIDINES AS SCAFFOLDS FOR PROTEASOME INHIBITORS AND MEDICINAL APPLICATIONS THEREOF | IKERCHEM, S.L. (ES) | 2015-08-27 | — | — | WO | claimed |
| EP-2910557-A1 | Enantiopure tetrasubstituted pyrrolidines as scaffolds for proteasome inhibitors and medicinal applications thereof | Ikerchem, S.L. (ES) | 2015-08-26 | — | — | EP | claimed |
| WO-2015124663-A1 | ENANTIOPURE TETRASUBSTITUTED PYRROLIDINES AS SCAFFOLDS FOR PROTEASOME INHIBITORS AND MEDICINAL APPLICATIONS THEREOF | IKERCHEM, S.L. (ES) | 2015-08-27 | — | — | WO | disclosed |
| EP-2910557-A1 | Enantiopure tetrasubstituted pyrrolidines as scaffolds for proteasome inhibitors and medicinal applications thereof | Ikerchem, S.L. (ES) | 2015-08-26 | — | — | EP | disclosed |