SCHEMBL17022644

SCHEMBL17022644

Brc1cc2c3ccsc3c(Br)cc2c2ccsc12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17022645 0.80 PARP1 (0.32) DYRK1A
SCHEMBL16005008 0.76 NEK1 (0.30)
SCHEMBL13280423 0.74 PARP1 (0.33) DYRK1A
SCHEMBL12275227 0.74 DYRK1A (0.33) DYRK1A
SCHEMBL2236457 0.70 DYRK1A (0.34) DYRK1A
SCHEMBL6644638 0.70 DYRK1A (0.44) DYRK1A
SCHEMBL726779 0.70 MAPT (0.35) DYRK1A
SCHEMBL29681675 0.70 KDM4E (0.33)
SCHEMBL22122313 0.70 IDO1 (0.33)
SCHEMBL21625566 0.70 CYP1A2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9564604-B2 Fused polycyclic aromatic compounds, organic semiconductor material and thin film including the same, and method for producing an organic semiconductor device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-02-07 US disclosed
US-20150303383-A1 Novel Condensed Polycyclic Aromatic Compound And Use Thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-10-22 US disclosed
EP-2910556-A1 NOVEL CONDENSED POLYCYCLIC AROMATIC COMPOUND AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2015-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150303383-A1 Novel Condensed Polycyclic Aromatic Compound And Use Thereof NCOA4, C9, NR1H3 DYRK1A 4588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.