Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 18/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023170 | 0.95 | FGFR3 (0.56) | FGFR3NPC1POLBF2F10 | |
| SCHEMBL17023137 | 0.95 | FGFR3 (0.57) | FGFR3NPC1POLBF2F10 | |
| SCHEMBL1126224 | 0.90 | FGFR3 (0.74) | FGFR3 | |
| SCHEMBL17023136 | 0.85 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL17023041 | 0.85 | FGFR3 (0.81) | FGFR3 | |
| SCHEMBL1126473 | 0.84 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL17023092 | 0.84 | FGFR3 (0.73) | FGFR3 | |
| SCHEMBL1126412 | 0.84 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL17023098 | 0.82 | FGFR3 (0.56) | FGFR3 | |
| SCHEMBL3313709 | 0.82 | FGFR3 (0.54) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |