Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023079 | 0.94 | FGFR3 (0.58) | FGFR3 | |
| SCHEMBL17023182 | 0.93 | FGFR3 (0.50) | FGFR3 | |
| SCHEMBL17023140 | 0.92 | FGFR3 (0.48) | FGFR3 | |
| SCHEMBL17023021 | 0.91 | FGFR3 (0.57) | FGFR3 | |
| SCHEMBL17023038 | 0.90 | FGFR3 (0.55) | FGFR3 | |
| SCHEMBL17023148 | 0.89 | FGFR3 (0.47) | FGFR3 | |
| SCHEMBL1126312 | 0.88 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL29564243 | 0.88 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL17023114 | 0.87 | FGFR3 (0.57) | FGFR3 | |
| SCHEMBL17023053 | 0.87 | FGFR3 (0.46) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |