Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 19/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023078 | 0.94 | FGFR3 (0.81) | FGFR3 | |
| SCHEMBL17023054 | 0.91 | FGFR3 (0.69) | FGFR3 | |
| SCHEMBL12678327 | 0.89 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL17023045 | 0.88 | FGFR3 (0.62) | FGFR3 | |
| SCHEMBL17023136 | 0.86 | FGFR3 (0.72) | FGFR3 | |
| SCHEMBL17023082 | 0.84 | FGFR3 (0.80) | FGFR3 | |
| SCHEMBL17023084 | 0.84 | FGFR3 (0.79) | FGFR3 | |
| SCHEMBL17023164 | 0.83 | FGFR3 (0.70) | FGFR3 | |
| SCHEMBL1126624 | 0.83 | FGFR3 (1.00) | FGFR3 | |
| SCHEMBL17023027 | 0.82 | FGFR3 (0.55) | FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282995-B1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-08-26 | — | — | EP | claimed |