Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.74 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.71 |
| ▸ | PIK3CB | P42338 | 17/20 | 0.71 |
| ▸ | PIK3CG | P48736 | 17/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2970607 | 0.90 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17361008 | 0.89 | PIK3CA (0.76) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL391282 | 0.88 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2462069 | 0.88 | PIK3CD (0.81) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2465953 | 0.87 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2466623 | 0.87 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL392597 | 0.87 | PIK3CD (0.78) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL387373 | 0.87 | PIK3CD (0.76) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL393696 | 0.86 | PIK3CD (0.81) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2469886 | 0.86 | PIK3CD (0.78) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812444-B1 | PHARMACEUTICAL COMPOUNDS | PIRAMED LTD (GB) | 2015-08-26 | — | — | EP | claimed |