Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023205 | 1.00 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL407282 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL402329 | 0.86 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL407106 | 0.86 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL407280 | 0.86 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL406132 | 0.73 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL405774 | 0.73 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL401527 | 0.73 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL406441 | 0.73 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL403928 | 0.71 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285787-B1 | 3-SUBSTITUTED PROPANAMINE COMPOUNDS | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-08-26 | — | — | EP | disclosed |