Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.71 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.71 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.71 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.71 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL8605319 | 1.00 | FFAR3 (0.71) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL28706434 | 0.93 | FFAR3 (0.71) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionic Acid SCHEMBL3662815 | 0.89 | — | — | |
| Propionic Acid SCHEMBL28699659 | 0.89 | FFAR3 (0.77) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Glycine SCHEMBL28449741 | 0.89 | — | — | |
| Glycine SCHEMBL2361724 | 0.89 | — | — | |
| Propionic Acid SCHEMBL28699660 | 0.89 | FFAR3 (0.77) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Propionamide SCHEMBL1947834 | 0.87 | GLRA1 (0.62) | FFAR3GLRA1SLC6A9OR51E2GABRR1 | |
| Glycine SCHEMBL2231959 | 0.86 | — | — | |
| Propionic Acid SCHEMBL10878598 | 0.86 | FFAR3 (0.71) | FFAR3GLRA1SLC6A9OR51E2GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025041353-A1 | BODY FLUID ANALYSIS METHOD AND SYSTEM | 株式会社日立ハイテクソリューションズ | 2025-02-27 | — | — | WO | disclosed |
| CN-107349867-A | Liquid thickener for surfactant system | 路博润高级材料公司 | 2017-11-17 | — | — | CN | disclosed |
| US-8895653-B2 | Acrylic adhesive composition, and pressure-sensitive adhesive sheet employing the same | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2014-11-25 | — | — | US | disclosed |
| CN-102534864-B | Preparation method of alkylation chitosan fiber | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2013-10-16 | — | — | CN | disclosed |
| EP-2202282-B1 | ACRYLIC ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET USING THE SAME | NAT INST FOR MATERIALS SCIENCE (JP) | 2013-03-27 | — | — | EP | disclosed |
| CN-102534864-A | Preparation method of alkylation chitosan fiber | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2012-07-04 | — | — | CN | disclosed |
| WO-2012006313-A2 | HERBICIDAL COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2012-01-12 | — | — | WO | disclosed |
| US-20110190436-A1 | ACRYLIC ADHESIVE COMPOSITION, AND PRESSURE-SENSITIVE ADHESIVE SHEET EMPLOYING THE SAME | NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20100292437-A1 | Polypeptides useful for appetite suppression | NELSON RALPH A | 2010-11-18 | — | — | US | disclosed |
| EP-2202282-A1 | ACRYLIC ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET USING THE SAME | National Institute for Materials Science (JP) | 2010-06-30 | — | — | EP | disclosed |
| US-7544662-B2 | Polypeptides useful for appetite suppression | CARLE DEVELOPMENT FOUNDATION (US) | 2009-06-09 | — | — | US | disclosed |
| US-20060276401-A1 | Polypeptides useful for appetite suppression | NELSON RALPH A | 2006-12-07 | — | — | US | disclosed |
| US-20060204589-A1 | Bear derived isolate and method | NELSON RALPH A | 2006-09-14 | — | — | US | disclosed |
| US-7060300-B2 | Bear derived isolate and method | CARLE DEVELOPMENT FOUNDATION (US) | 2006-06-13 | — | — | US | disclosed |
| US-6855337-B1 | Bear derived isolate and method | CARLE DEVELOPMENT FOUNDATION (US) | 2005-02-15 | — | — | US | disclosed |
| CN-1029325-C | Oil pipe with nickel-phosphorus alloy anti-corrosion coating and its producing method | SUN KENING (CN) | 1995-07-12 | — | — | CN | disclosed |
| CN-1089341-A | Oil pipe and manufacture method with nickel-phosphorus alloy anti-corrosion coating | SUN KENING (CN) | 1994-07-13 | — | — | CN | disclosed |