Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.59 |
| ▸ | EPAS1 | Q99814 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MAP2K3 | P46734 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325874 | 0.84 | KMT2A (0.67) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023890 | 0.83 | MEN1 (0.65) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023903 | 0.81 | HPGD (0.55) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023874 | 0.81 | KMT2A (0.59) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023878 | 0.81 | KMT2A (0.55) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023882 | 0.81 | HIF1A (0.47) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023891 | 0.80 | KMT2A (0.57) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023897 | 0.79 | KDM4E (0.50) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023886 | 0.77 | KMT2A (0.51) | HIF1AEPAS1KMT2AMEN1GAA | |
| SCHEMBL17023871 | 0.77 | KMT2A (0.51) | HIF1AEPAS1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10847726-B2 | Imidizo derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2020-11-24 | — | — | US | claimed |
| US-20190131538-A1 | IMIDIZO DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2019-05-02 | — | — | US | claimed |
| US-10847726-B2 | Imidizo derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2020-11-24 | — | — | US | disclosed |
| US-10847726-B2 | Imidizo derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190131538-A1 | IMIDIZO DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2019-05-02 | — | — | US | disclosed |
| US-20190131538-A1 | IMIDIZO DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2019-05-02 | — | — | US | disclosed |
| US-20150243896-A1 | IMIDAZO DERIVATIVES | ARMY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2015-08-27 | — | — | US | disclosed |
| US-20150243896-A1 | IMIDAZO DERIVATIVES | ARMY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2015-08-27 | — | — | US | disclosed |
| US-20150243896-A1 | IMIDAZO DERIVATIVES | ARMY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190131538-A1 | IMIDIZO DERIVATIVES | IKZF1, IKZF3, IKZF2 | HIF1A 4237/4885EPAS1 2959/4885KMT2A 1089/4885 |
| US-10847726-B2 | Imidizo derivatives | IKZF1, IKZF3, IKZF2 | HIF1A 4237/4885EPAS1 2959/4885KMT2A 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.