Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9101450 | 0.93 | ABCB1 (0.56) | ABCB1KCNK3KCNK9 | |
| SCHEMBL27237889 | 0.92 | ABCB1 (0.45) | ABCB1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL17025770 | 0.91 | ABCB1 (0.40) | ABCB1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL27237886 | 0.90 | ABCB1 (0.44) | ABCB1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL17527274 | 0.88 | ABCB1 (0.43) | ABCB1EEDRBBP4SUZ12EZH2 | |
| SCHEMBL17025766 | 0.85 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL22363210 | 0.85 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL19946425 | 0.85 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL17025797 | 0.83 | ABCB1 (0.52) | ABCB1 | |
| SCHEMBL17025742 | 0.83 | ABCB1 (0.39) | ABCB1EEDRBBP4SUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150240244-A1 | BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT (GB) | 2015-08-27 | — | — | US | claimed |
| EP-4382913-A2 | MODULATING EXPRESSION OF POLYPEPTIDES VIA NEW GENE SWITCH EXPRESSION SYSTEMS | Precigen, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |