SCHEMBL1702645

SCHEMBL1702645

CCc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(CC)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.54
CHKA P35790 4/20 0.47
TAAR1 Q96RJ0 2/20 0.47
ALDH1A1 P00352 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CNR2 P34972 2/20 0.41
TSHR P16473 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
KCNH2 Q12809 1/20 0.40
LPL P06858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12799485 1.00 TP53 (0.54) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL14650368 1.00 TP53 (0.54) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL19826352 1.00 TP53 (0.54) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL17987005 0.98 TP53 (0.52) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL14011838 0.98 TP53 (0.52) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL5008610 0.96 TP53 (0.54) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL17735819 0.96 TP53 (0.54) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL17986988 0.96 TP53 (0.54) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL13855250 0.96 TP53 (0.54) TP53CHKATAAR1ALDH1A1L3MBTL1
SCHEMBL23264336 0.93 TP53 (0.62) TP53CHKATAAR1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US claimed
US-7267917-B2 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2007-09-11 US claimed
US-20060063080-A1 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2006-03-23 US claimed
EP-0486038-B1 Electrophotographic photoreceptor IDEMITSU KOSAN CO (JP) 1996-10-16 EP claimed
US-5213924-A Copolymers, improved mechanical strength, hardness IDEMITSU KOSAN CO. LTD. (JP) 1993-05-25 US claimed
EP-3553151-A1 PHOSPHORESCENT SUBSTANCE AND PHOSPHORESCENT ELEMENT Kyushu University, National University Corporation (JP) 2019-10-16 EP disclosed
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US disclosed
US-8343381-B1 Hole transport composition E I DU PONT DE NEMOURS AND COMPANY (US) 2013-01-01 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-8120719-B2 Photo-addressable display medium and photo-addressable display device FUJI XEROX CO., LTD. (JP) 2012-02-21 US disclosed
US-8120719-B2 Photo-addressable display medium and photo-addressable display device FUJI XEROX CO., LTD. (JP) 2012-02-21 US disclosed
US-7903324-B2 Optical switching element and photoaddressable display medium using the same FUJI XEROX CO., LTD. (JP) 2011-03-08 US disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
US-4536457-A Migration imaging process XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4346158-A Imaging system with a diamine charge transport material in a polycarbonate resin XEROX CORPORATION (US) 1982-08-24 US disclosed
US-4314012-A Photoconductive reflex exposure member XEROX CORPORATION (US) 1982-02-02 US disclosed
US-4265990-A Imaging system with a diamine charge transport material in a polycarbonate resin XEROX CORPORATION (US) 1981-05-05 US disclosed