Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447555 | 0.83 | CRBN (0.40) | CRBN | |
| SCHEMBL1702711 | 0.81 | CRBN (0.42) | CRBN | |
| SCHEMBL1702739 | 0.74 | CRBN (0.55) | CRBN | |
| SCHEMBL2447558 | 0.73 | CRBN (0.37) | CRBN | |
| SCHEMBL1702654 | 0.73 | CYP3A4 (0.33) | — | |
| SCHEMBL1702807 | 0.67 | CRBN (0.47) | CRBN | |
| SCHEMBL12302371 | 0.67 | KDM4E (0.33) | — | |
| SCHEMBL2448595 | 0.65 | AURKA (0.36) | CRBN | |
| SCHEMBL1703017 | 0.65 | IRAK1 (0.35) | CRBN | |
| SCHEMBL2452207 | 0.65 | IRAK1 (0.35) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440528-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010142656-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |