SCHEMBL17027596

SCHEMBL17027596

CCCCCC[C@@H]1CC=CC(=O)O1

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDCD4 Q53EL6 2/20 0.58
CYP1A2 P05177 2/20 0.50
PPARG P37231 2/20 0.44
ALDH1A1 P00352 1/20 0.44
GRM2 Q14416 10/20 0.43
EPHX1 P07099 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16320605 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL16341541 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL16341360 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL16340799 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL16341658 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL4651591 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL16341423 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL16340997 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL3662367 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2
SCHEMBL31711153 1.00 PDCD4 (0.58) PDCD4CYP1A2PPARGALDH1A1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3107904-B1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 SCIENCE INC (US) 2019-06-05 EP claimed
US-10011582-B2 Substituted delta-lactones and methods of preparing same P2 SCIENCE, INC. (US) 2018-07-03 US claimed
US-20170057940-A1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 SCIENCE, INC. 2017-03-02 US claimed
EP-3107904-A1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 Science, Inc. (US) 2016-12-28 EP claimed
WO-2015126936-A1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 SCIENCE, INC. (US) 2015-08-27 WO claimed
EP-3107904-B1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 SCIENCE INC (US) 2019-06-05 EP disclosed
US-10011582-B2 Substituted delta-lactones and methods of preparing same P2 SCIENCE, INC. (US) 2018-07-03 US disclosed
US-20170057940-A1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 SCIENCE, INC. 2017-03-02 US disclosed
EP-3107904-A1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 Science, Inc. (US) 2016-12-28 EP disclosed
WO-2015126936-A1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME P2 SCIENCE, INC. (US) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10011582-B2 Substituted delta-lactones and methods of preparing same FASN, EBP, LSS PDCD4 3770/4885CYP1A2 302/4885PPARG 79/4885
US-20170057940-A1 SUBSTITUTED DELTA-LACTONES AND METHODS OF PREPARING SAME FASN, EBP, LSS PDCD4 3770/4885CYP1A2 302/4885PPARG 79/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.