Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17021494 | 1.00 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17007229 | 1.00 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17021455 | 0.90 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17007350 | 0.90 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17007257 | 0.87 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17166370 | 0.87 | HCRTR1 (0.76) | HCRTR1HCRTR2 | |
| SCHEMBL17017384 | 0.87 | HCRTR1 (0.76) | HCRTR1HCRTR2 | |
| SCHEMBL17007396 | 0.87 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17007118 | 0.86 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17007335 | 0.86 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107898-A1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015124932-A1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA CAMBRIDGE LIMITED (GB) | 2015-08-27 | — | — | WO | disclosed |