Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286025 | 0.71 | KDM4E (0.59) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3082762 | 0.69 | NPC1 (0.42) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL571374 | 0.69 | HDAC8 (0.50) | KDM4ENPC1ALDH1A1MAPTDYRK1A | |
| SCHEMBL3135899 | 0.69 | KDM4E (0.62) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4059081 | 0.68 | CYP1A2 (0.57) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8491506 | 0.67 | KDM4E (0.39) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5904803 | 0.67 | DYRK1A (0.37) | DYRK1AIMPDH2PIM1PRMT5WDR77 | |
| SCHEMBL2744787 | 0.65 | KDM4E (0.49) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL27634717 | 0.65 | KDM4E (0.49) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL31301177 | 0.65 | KDM4E (0.41) | KDM4ENPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015124606-A1 | N-SUBSTITUTED IMINO HETEROCYCLIC COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-27 | — | — | WO | disclosed |