SCHEMBL17029239

SCHEMBL17029239

Cc1cccc(-c2cn(C)c(=O)c3ccccc23)c1

nearest known ligand 0.77

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 1/20 0.77
BRD7 Q9NPI1 1/20 0.77
BRD4 O60885 19/20 0.70
BRDT Q58F21 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19930675 0.86 BRD4 (0.68) BRD9BRD7BRD4
SCHEMBL25043364 0.84 BRD4 (0.66) BRD9BRD7BRD4
SCHEMBL25043102 0.83 BRD4 (0.65) BRD9BRD7BRD4
SCHEMBL6334276 0.83 BRD4 (1.00) BRD9BRD7BRD4BRDT
SCHEMBL16650888 0.83 BRD4 (1.00) BRD9BRD7BRD4BRDT
SCHEMBL29849131 0.83 BRD4 (1.00) BRD9BRD7BRD4BRDT
SCHEMBL9919100 0.83 BRD4 (0.73) BRD9BRD7BRD4
SCHEMBL16651898 0.80 BRD4 (1.00) BRD9BRD7BRD4BRDT
SCHEMBL29848894 0.80 BRD4 (1.00) BRD9BRD7BRD4BRDT
SCHEMBL16650880 0.80 BRD4 (1.00) BRD9BRD7BRD4BRDT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134364-A2 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2023-02-15 EP disclosed
US-9115114-B2 Bromodomain inhibitors Quanticel Pharmaceuticals, Inc. (US) 2015-08-25 US disclosed