Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | PPARA | Q07869 | 7/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17029312 | 0.88 | MCL1 (0.37) | PPARGPPARAMCL1ACMSDENPP3 | |
| SCHEMBL15424779 | 0.88 | CD274 (0.41) | TLR8CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18019644 | 0.86 | CD274 (0.38) | ENPP3TLR8CA12CA1CA2 | |
| SCHEMBL16135115 | 0.84 | CD274 (0.38) | TLR8PDCD1CD274 | |
| SCHEMBL20124391 | 0.77 | MCL1 (0.53) | PPARGPPARAMCL1ACMSDENPP3 | |
| SCHEMBL31742566 | 0.75 | MCL1 (0.54) | PPARGPPARAMCL1ACMSDENPP3 | |
| SCHEMBL20405143 | 0.75 | CA12 (0.41) | PPARGPPARAMCL1ACMSDENPP3 | |
| SCHEMBL12037333 | 0.74 | MCL1 (0.40) | MCL1ACMSDCA12CA1CA2 | |
| SCHEMBL12037138 | 0.74 | MCL1 (0.40) | MCL1ACMSDENPP3ENPP1CA12 | |
| SCHEMBL20407098 | 0.74 | CYP1A2 (0.48) | CYP2C9CYP2C19CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9118017-B2 | Host compounds for red phosphorescent OLEDs | UNIVERSAL DISPLAY CORPORATION (US) | 2015-08-25 | — | — | US | disclosed |