⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860749 | 0.82 | SLC28A1 (0.32) | — | |
| SCHEMBL15782468 | 0.82 | SLC28A1 (0.32) | — | |
| SCHEMBL17807707 | 0.82 | SLC28A1 (0.32) | — | |
| SCHEMBL10238922 | 0.82 | SLC28A1 (0.32) | — | |
| SCHEMBL17054345 | 0.79 | SLC28A1 (0.41) | — | |
| SCHEMBL16647500 | 0.77 | SLC28A1 (0.32) | — | |
| SCHEMBL1591858 | 0.74 | SLC28A1 (0.31) | — | |
| SCHEMBL22503385 | 0.74 | SLC28A1 (0.31) | — | |
| SCHEMBL15765635 | 0.74 | SLC28A1 (0.31) | — | |
| SCHEMBL14946358 | 0.72 | SLC28A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913337-A1 | N-[(2'R)-2'-DEOXY-2'-FLUORO-2'-METHYL-P-PHENYL-5'-URIDYLYL]-L-ALANINE 1-METHYLETHYL ESTER AND PROCESS FOR ITS PRODUCTION | Gilead Pharmasset LLC (US) | 2015-09-02 | — | — | EP | disclosed |
| EP-2910562-A1 | N-[(2'r)-2'-deoxy-2 '-fluoro-2'-methyl-p-phenyl-5 '-uridylyl]-l-alanine 1-methylethyl ester in crystalline form | Gilead Pharmasset LLC (US) | 2015-08-26 | — | — | EP | disclosed |