Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404558 | 0.84 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3CYP17A1CYP2C9 | |
| SCHEMBL407110 | 0.81 | SLC6A4 (0.63) | SLC6A2SLC6A4SLC6A3CYP2C9CYP2C19 | |
| SCHEMBL407017 | 0.81 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3UTS2RCYP17A1 | |
| SCHEMBL407579 | 0.78 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL406307 | 0.76 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL405209 | 0.76 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP17A1CYP2C9 | |
| SCHEMBL405227 | 0.76 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 | |
| SCHEMBL405891 | 0.75 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3UTS2RHTR2A | |
| SCHEMBL402249 | 0.75 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL406496 | 0.75 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285787-B1 | 3-SUBSTITUTED PROPANAMINE COMPOUNDS | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-08-26 | — | — | EP | disclosed |