Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 13/20 | 0.77 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | LYN | P07948 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12982658 | 0.87 | MAPK1 (1.00) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL17030269 | 0.81 | MAPK1 (0.77) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL17030249 | 0.80 | MAPK1 (0.67) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL17030287 | 0.77 | MAPK1 (0.60) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL17030278 | 0.76 | MAPK1 (0.59) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL17030265 | 0.75 | MAPK1 (0.57) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL17030251 | 0.75 | MAPK1 (0.59) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL12970769 | 0.72 | MAPK1 (1.00) | MAPK1 | |
| SCHEMBL12979934 | 0.72 | MAPK1 (0.64) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL14506616 | 0.72 | MAPK1 (1.00) | MAPK1PIK3CAMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694067-B1 | PYRIDOPYRAZINE DERIVATIVES AND THEIR USE | TERNA ZENTARIS GMBH (DE) | 2015-08-26 | — | — | EP | disclosed |