Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 20/20 | 0.84 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.71 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.71 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.71 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12970878 | 0.91 | MAPK1 (1.00) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL12971139 | 0.91 | MAPK1 (0.84) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL13191753 | 0.90 | MAPK1 (0.83) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL12971081 | 0.90 | MAPK1 (0.82) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL12970824 | 0.88 | MAPK1 (0.80) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL12970848 | 0.88 | MAPK1 (0.80) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL12970911 | 0.87 | MAPK1 (0.78) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL12970745 | 0.87 | MAPK1 (0.77) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL13173608 | 0.87 | MAPK1 (0.82) | MAPK1PIK3CAMAPK8MAPK9MAPK10 | |
| SCHEMBL4675759 | 0.86 | MAPK1 (0.77) | MAPK1PIK3CAMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694067-B1 | PYRIDOPYRAZINE DERIVATIVES AND THEIR USE | TERNA ZENTARIS GMBH (DE) | 2015-08-26 | — | — | EP | disclosed |