SCHEMBL17030460

SCHEMBL17030460

c1ccc(-n2c3ccccc3c3cc(-c4nc(-n5c6ccccc6c6cc(-n7c8ccccc8c8ccccc87)ccc65)c5sc6ccccc6c5n4)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGER4 P35408 1/20 0.35
HRH4 Q9H3N8 2/20 0.34
PIK3CA P42336 2/20 0.33
TNKS O95271 2/20 0.33
TNKS2 Q9H2K2 2/20 0.33
HTR2C P28335 1/20 0.33
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HTR1A P08908 2/20 0.30
HTR7 P34969 2/20 0.30
PDE1B Q01064 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16905647 0.97 ATM (0.40) ATMKDM4EL3MBTL1PTGER4HRH4
SCHEMBL17030462 0.93 PIK3CA (0.39) ATMKDM4EL3MBTL1HRH4PIK3CA
SCHEMBL20670196 0.92 KDM4E (0.36) ATMKDM4EL3MBTL1PTGER4HRH4
SCHEMBL17087618 0.92 KDM4E (0.36) ATMKDM4EL3MBTL1PTGER4HRH4
SCHEMBL18273056 0.90 ATM (0.40) ATMKDM4EL3MBTL1HRH4PIK3CA
SCHEMBL20670231 0.90 LIMK1 (0.41) ATMKDM4EL3MBTL1PTGER4PIK3CA
SCHEMBL20670230 0.89 KDM4E (0.34) ATMKDM4EL3MBTL1PTGER4HRH4
SCHEMBL16905712 0.89 HRH4 (0.39) ATMKDM4EL3MBTL1HRH4PIK3CA
SCHEMBL19247897 0.88 ATM (0.40) ATMKDM4EL3MBTL1HRH4PIK3CA
SCHEMBL16905710 0.88 HRH4 (0.37) ATMKDM4EL3MBTL1HRH4PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2910555-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2019-03-27 EP disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 US disclosed
EP-2910555-A1 Organic electroluminescent materials and devices Universal Display Corporation (US) 2015-08-26 EP disclosed