Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20203089 | 0.89 | KDM4E (0.50) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL10111055 | 0.86 | KDM4E (0.46) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL10111060 | 0.85 | KDM4E (0.49) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL20203091 | 0.85 | KDM4E (0.45) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL29622127 | 0.83 | KDM4E (0.62) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL888033 | 0.83 | KDM4E (0.62) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL18121355 | 0.82 | AKT1 (0.49) | KDM4EATML3MBTL1AVPR1AALDH1A1 | |
| SCHEMBL2744593 | 0.82 | KDM4E (0.61) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL18109216 | 0.82 | KDM4E (0.49) | KDM4EATML3MBTL1AVPR1AHSD17B10 | |
| SCHEMBL10111066 | 0.82 | KDM4E (0.56) | KDM4EATML3MBTL1AVPR1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170365790-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-12-21 | — | — | US | disclosed |
| US-20170365790-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-12-21 | — | — | US | disclosed |
| US-20150243902-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-08-27 | — | — | US | disclosed |
| US-20150243902-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170365790-A1 | CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE | CYP2C9, CYP2C19, INTS9 | KDM4E 2376/4885ATM 2967/4885L3MBTL1 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.