Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.76 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962530 | 0.91 | ALK (0.68) | ALKKITKDR | |
| SCHEMBL898262 | 0.91 | ALK (0.71) | ALKKITKDR | |
| SCHEMBL898132 | 0.90 | ALK (0.81) | ALKKITKDR | |
| SCHEMBL898261 | 0.88 | ALK (0.68) | ALKKITKDR | |
| SCHEMBL29962708 | 0.88 | ALK (0.78) | ALKKITKDR | |
| SCHEMBL898349 | 0.88 | ALK (0.84) | ALKKITKDR | |
| SCHEMBL897456 | 0.87 | ALK (0.88) | ALKKITKDR | |
| SCHEMBL897503 | 0.86 | ALK (0.94) | ALKKITKDR | |
| SCHEMBL897820 | 0.86 | ALK (1.00) | ALKKITKDR | |
| SCHEMBL897440 | 0.83 | ALK (0.65) | ALKKITKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441753-A1 | TETRACYCLIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-04-18 | — | — | EP | disclosed |