⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422568 | 1.00 | — | — | |
| SCHEMBL6141308 | 0.98 | TSHR (0.42) | — | |
| SCHEMBL8592154 | 0.98 | TSHR (0.42) | — | |
| SCHEMBL6141195 | 0.92 | — | — | |
| SCHEMBL5735736 | 0.81 | — | — | |
| SCHEMBL311220 | 0.79 | — | — | |
| SCHEMBL9942449 | 0.78 | — | — | |
| Ammonia Solution, Strong SCHEMBL3349086 | 0.77 | — | — | |
| SCHEMBL826318 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL50150 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6662 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239752-A1 | BICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-07-18 | — | — | US | claimed |
| EP-3383377-B1 | COMPOUNDS AND METHODS FOR INHIBITING PRODUCTION OF TRIMETHYLAMINE | PROCTER & GAMBLE (US) | 2024-04-17 | — | — | EP | claimed |
| WO-2023244639-A1 | METHODS OF PREDICTING CNS CANCER RESPONSE TO TREATMENT WITH EGFR INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-12-21 | — | — | WO | claimed |
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | claimed |
| CN-116077665-A | Compounds for the treatment of ophthalmic diseases and disorders | 奇奥拉制药股份有限公司 | 2023-05-09 | — | — | CN | claimed |
| WO-2023067322-A1 | TRICYCLIC GPR65 MODULATORS | Pathios Therapeutics Limited (GB) | 2023-04-27 | — | — | WO | claimed |
| US-20230110003-A1 | PIPERIDINE DERIVATIVES AND COMPOSITIONS FOR THE INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) | Valo Health, LLC | 2023-04-13 | — | — | US | claimed |
| US-11597727-B2 | Inhibitors of integrin alpha 2 beta 1 and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-07 | — | — | US | claimed |
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | claimed |
| US-20210387986-A1 | INHIBITORS OF INTEGRIN ALPHA 2 BETA 1 AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-16 | — | — | US | claimed |
| EP-0044214-A2 | Novel phosphorous esters of cyanohydrins, pesticidal compositions including same, and methods of controlling pests using same | UNION CARBIDE CORPORATION (US) | 1982-01-20 | — | — | EP | claimed |
| US-4170479-A | SILVER HALIDE EMULSION LAYERS OF DIFFERING PHOTOSENSITIVITY | FUJI PHOTO FILM CO., LTD. (JP) | 1979-10-09 | — | — | US | claimed |
| US-4115115-A | Crystallization of selenium in polymer matrices via in situ generation of organic crystalline nucleation sites | XEROX CORPORATION (US) | 1978-09-19 | — | — | US | claimed |
| US-4097408-A | FROM DIHYDOPEROXIDE AND CARBONYL COMPOUND, POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1978-06-27 | — | — | US | claimed |
| US-4050939-A | DISPERSION IN POLYMER MATRIX | XEROX CORPORATION (US) | 1977-09-27 | — | — | US | claimed |
| US-4050937-A | Imagewise exposing and heating a microimaging film containing an organo diselenide, a tertiary phosphine or phosphite and an organic peroxide | XEROX CORPORATION (US) | 1977-09-27 | — | — | US | claimed |
| US-4047947-A | Process for preparation of transparencies by selective decomposition of an organoselenium compound in a polymeric matrix | XEROX CORPORATION (US) | 1977-09-13 | — | — | US | claimed |
| US-4030993-A | SELENIUM | XEROX CORPORATION (US) | 1977-06-21 | — | — | US | claimed |
| US-3994791-A | FORMING SELENIUM FROM ORGANO-SELENIUM COMPOUNDS | XEROX CORPORATION (US) | 1976-11-30 | — | — | US | claimed |
| US-3967964-A | Photosensitive film comprising an organopolyselenide and an organomercury compound | XEROX CORPORATION (US) | 1976-07-06 | — | — | US | claimed |