Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16381727 | 0.80 | SGPL1 (0.36) | SGPL1LMNA | |
| SCHEMBL16740884 | 0.76 | SGPL1 (0.39) | SGPL1 | |
| SCHEMBL15868232 | 0.75 | SGPL1 (0.32) | SGPL1 | |
| SCHEMBL21524933 | 0.75 | — | — | |
| SCHEMBL21524935 | 0.75 | — | — | |
| SCHEMBL17316269 | 0.72 | — | — | |
| SCHEMBL16369037 | 0.71 | SGPL1 (0.36) | SGPL1LMNA | |
| SCHEMBL15176857 | 0.71 | SGPL1 (0.36) | SGPL1LMNA | |
| SCHEMBL18719988 | 0.70 | SGPL1 (0.34) | SGPL1 | |
| SCHEMBL15738811 | 0.69 | CHRM1 (0.40) | SGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015124941-A1 | PYRAZOLO[1,5-A]PYRIMIDINE-5,7-DIAMINE COMPOUNDS AS CDK INHIBITORS AND THEIR THERAPEUTIC USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-08-27 | — | — | WO | disclosed |