SCHEMBL17032736

SCHEMBL17032736

N#Cc1ccc2c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)ccc3n(-c3ccc(-c4ccccc4)cc3)c2c1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ PTGER4 P35408 1/20 0.38
▸ G6PD P11413 2/20 0.38
▸ TSPO P30536 1/20 0.37
▸ HDAC4 P56524 1/20 0.37
▸ TDP2 O95551 3/20 0.37
▸ PGR P06401 2/20 0.36
▸ KMT2A Q03164 1/20 0.35
▸ GABRA1 P14867 1/20 0.35
▸ GABRG2 P18507 1/20 0.35
▸ GABRB3 P28472 1/20 0.35
▸ GABRA5 P31644 1/20 0.35
▸ GABRA3 P34903 1/20 0.35
▸ IL1R1 P14778 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17034492 0.99 KDM4E (0.45) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL18767465 0.99 KDM4E (0.44) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL18623543 0.99 KDM4E (0.47) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL18623545 0.99 KDM4E (0.44) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL18633415 0.99 KDM4E (0.47) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL18633416 0.99 KDM4E (0.44) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL17178539 0.97 KDM4E (0.44) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL18792458 0.97 KDM4E (0.44) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL17660975 0.97 KDM4E (0.49) KDM4EATML3MBTL1PTGER4G6PD
SCHEMBL18633414 0.96 ATM (0.43) KDM4EATML3MBTL1PTGER4G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 — — US disclosed
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 — — US disclosed
US-10403825-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 — — US disclosed
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10403825-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP KDM4E 4278/4885ATM 4635/4885L3MBTL1 930/4885
US-20150243903-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP KDM4E 4278/4885ATM 4635/4885L3MBTL1 930/4885
US-20230131934-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP KDM4E 4278/4885ATM 4635/4885L3MBTL1 930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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