SCHEMBL17033385

SCHEMBL17033385

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5ccc6c(cc7c8ccccc8c8ccccc8n76)c54)c3)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
PDE10A Q9Y233 1/20 0.32
CYP19A1 P11511 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033435 0.90 KMT2A (0.37) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17033426 0.88 ATM (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17033602 0.88 KDM4E (0.33) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17864153 0.87 KDM4E (0.36) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17033725 0.87 MEN1 (0.34) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL22596046 0.87 KDM4E (0.44) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17033382 0.87 KDM4E (0.37) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL16067165 0.86 KDM4E (0.32) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17809197 0.86 KDM4E (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17809170 0.86 KDM4E (0.39) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed